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KMID : 1039920130200010106
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Neonatal Medicine
2013 Volume.20 No. 1 p.106 ~ p.112
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Partial Seizures Manifesting as Apnea Only in Preterm Infant
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Jun Ja-Kyung
Moon Cheong-Jun
Kim Soon-Ju
Youn Young-Ah
Lee Ju-Young
Lee Hyun-Seung
Lee Jung-Hyun
Sung In-Kyung
Kim So-Young
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Abstract
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Purpose: Extremely-low-birth-weight infants (ELBWIs), especially those ≤24 gestational weeks (GW), presented extremes in IWL and changes of water balance. The purpose of the present study was to retrospectively investigate fluid and electrolyte balance in infants of ≤24-GW during the first postnatal week under high humidification.
Methods: Medical records of extremely-low-birth-weight infants (ELBWIs) who were born and admitted to the Neonatal Intensive Care Unit at Samsung Medical Center during March 2004-September 2010 were reviewed. Fluid intake, urine output, insensible water loss (IWL), and electrolyte balance of 22-GW (n=14), 23-GW (n=40), and 24-GW (n=67) infants nursed in high humidity (95%) were compared with ≥26-GW (n=65) infants nursed in 60% humidity.
Results: Survival rate until discharge was 33%, 82%, 75%, and 89.3% in 22-GW, 23-GW, 24-GW, and ≥26-GW infants, respectively. Fluid intake and IWL was higher in 22-GW and 23-WG, but not different in 24-GW, than in ≥26-GW infants. At postnatal days (P) 3-5, the urine output was significantly lower in ≥26-GW infants than in the other age groups. Serum sodium level was significantly higher in 22-, 23-, and 24-GW (P1-2) than in ≥26-GW infants. Hypernatremia (>150 mEq/dl sodium) was more frequent in 22-GW (71%), 23-GW (41%), and 24-GW (21%) than in ≥26-GW infants (14%).
Conclusion: High-humidity environments significantly decreased fluid intake and improved electrolyte imbalance in 24-GW, but not 22- and 23-GW, infants. Increased IWL in the latter might be related to more immature skin, and implicates the need for additional nurturing conditions.
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KEYWORD
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Electrolytes, Extremely-low-birth-weight infant, Humidity, Insensible water loss
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